Is vaping harder to quit than smoking? What the evidence says
We found no trial that answers this head to head. Here is what the evidence does show about vaping sessions, nicotine delivery and dependence, what it doesn't, and what that means for your plan.
本文为英文。
Whether vaping is harder to quit than smoking is a fair question, and we found no trial that answers it directly. What exists is a set of pieces: how a vaping session compares with a cigarette, how much nicotine some devices deliver, how dependent people report feeling, and a few trials of quitting vaping that are small or short. This guide lays out those pieces, marks where the evidence runs out, and ends with what that means for a plan.
How a vaping session compares with a cigarette#
In one study of Italian adults, people who smoke and used a prototype e-cigarette had sessions that averaged about 18 minutes, against about 5 minutes for a cigarette. They took about 59 puffs against 17.1 The authors say the longer sessions "may be attributable to differences in product operation," and the device was a prototype, not a retail vape. The puffs themselves looked similar: mean puff volume was 41.6 mL for the e-cigarette and 41.3 mL for the cigarette.1
The same study found that mouth-level nicotine exposure was lower for the e-cigarette than for the cigarette. That is a useful reminder that delivery depends on the product, and that a single study with one device cannot stand in for every vape on sale.1
The practical point is the end of a session. A cigarette is a fixed unit that burns down. A vape has no built-in end point, so how many puffs you take in a session depends more on the device and on you. That is harder to see from the inside, and it is one reason to count.
Nicotine delivery: some devices get close to cigarettes#
In a crossover study of 20 dual users, people who both smoke and vape, a pod vape with 59 mg/mL nicotine gave a peak nicotine level of 20.4 ng/ml. The participants' own cigarettes gave 19.2 ng/ml. The peak came at about 4 minutes for the pod and 6 minutes for the cigarette.2 The authors say the product's profile "was close to the PK profile of cigarettes." They also say the nicotine salt formulation "seems to blunt sensory clues to nicotine intake."2
The study was funded by Cancer Research UK, it was small, and it tested one product: a US version with more nicotine in the liquid than the version sold in the EU. The authors' conclusion covers both sides. The profile "could be more effective than other EC products in helping smokers to quit smoking, but it may also have a higher potential to generate regular use in non-smokers."2
Dependence: what people report#
A small study from Poland compared three groups of 30 young, highly educated adults: cigarette smokers, exclusive e-cigarette users, and dual users. Dependence was measured with the Fagerström test, and with an adapted version for e-cigarettes. The authors reported that "The nicotine dependence levels measured with FTND were over two times higher among e-cigarette users (mean 3.5) compared to traditional tobacco smokers (mean 1.6; p < 0.001)."3 Among dual users, the score was higher when they vaped (mean 4.7) than when they smoked (mean 3.2).3
Two cautions. The groups are small, and the test was adapted for e-cigarettes, so the two scores are not measured on exactly the same scale. Read it as one more sign that dependence on vaping deserves attention, not as a ranking of the two habits.
What the trials of quitting show#
The cigarette side has a large trial base. Cochrane's 2018 review of nicotine replacement in smokers identified 136 studies, and 133 of them, with 64,640 participants, contributed to the main comparison.4 The vaping side is much thinner. The RACGP guidance says: "Currently there is limited research on interventions specifically targeting vaping cessation."5 A 2026 narrative review concluded that evidence for NRT in vaping "remains inconclusive because of the small number of available studies and relatively short follow-up durations."6
The clearest vaping result comes from a prescription medicine. In a 2025 trial of 261 people, average age 21.4, continuous abstinence in weeks 9 to 12 was 51% with varenicline and 14% with placebo. The authors concluded that varenicline with behavioural counseling "increased vaping abstinence in youth who vape nicotine and do not regularly smoke tobacco."7 That is a trial of young people, not a comparison with smoking. We found no trial that compares how hard it is to quit vaping with how hard it is to quit smoking.
Cigarettes and vapes, side by side#
Every number in the table appears in the sections above, with its source. The last column is the one that matters for planning: what the evidence does not yet tell us.
| Factor | Cigarettes | Vapes | We don't know yet |
|---|---|---|---|
| Session end | A fixed unit that burns down | No built-in end point; the Italian prototype sessions averaged about 18 minutes against about 5 for a cigarette | How session length changes with everyday use, outside a lab |
| Puffs per session | About 17 in the Italian study | About 59 in the same study, with the authors noting device operation may explain part of it | Whether this holds for retail devices |
| Nicotine delivery | Peak of 19.2 ng/ml in the pod vape study | Peak of 20.4 ng/ml for a 59 mg/mL pod in the same study; the Italian prototype had lower mouth-level nicotine exposure than a cigarette | Delivery across the many devices and strengths on sale |
| Dependence score | Mean 1.6 on the Fagerström test in the Polish study | Mean 3.5 for exclusive e-cigarette users in the same study | Whether the adapted scale measures the same thing in both |
| Research on quitting | Large trial base, including NRT in smokers | A few small or short trials, and one prescription trial in young people | Whether vaping is harder to quit over the long run |
| Cost per day | Depends on what you buy and how often | Depends on the device, the pods or liquid, and use; the vaping cost calculator works through an example | How your own use compares once you count it |
| Where you can use it | Rules vary by place | Rules vary by place, and by country | Whether local rules change how people use vapes |
What this means for your plan#
If the evidence can't say whether vaping is harder to quit, the useful question is what you can measure. Three things follow from what we have.
- Count the puffs, because a vape session has no natural stopping point. A count per day gives you a number to cut. How to track your vape puffs covers how to do it.
- Get help with the nicotine as well as the habit. The RACGP guidance says the first-line approach for vaping is behavioural support, with medicine when it is needed.5 A step-down plan is in how to taper off vaping with a step-down plan.
- Expect withdrawal to come in stages. Vape withdrawal timeline sets out what tends to happen and when, so a bad week doesn't look like failure.
We built ExHale around the part of this you can measure: your own use. You log each puff and craving with one tap, so a vape session with no natural end point becomes a number on your Stats screen. Your quit plan starts with a calibration week, then steps your nicotine down weekly, adapting to what you actually log. If you smoke as well as vape, ExHale covers cigarettes too, with a plan made for smokers. When a craving hits, the craving SOS opens breathing exercises and quick minigames, or a turn-based battle with Reddington, your pixel quit buddy.
For the whole plan, read how to quit vaping.
Questions about vaping and quitting#
Is vaping harder to quit than smoking?
No trial has compared the two directly, so there is no firm yes or no. Some devices deliver nicotine close to a cigarette, and in small studies people who vape score higher on a nicotine dependence test than people who smoke. Vaping sessions are also less bounded. Trials of quitting vaping are few and small. Treat this as a reason to plan carefully, not as a verdict.
Why might vaping be more addictive than smoking?
Some high-strength nicotine salt devices can deliver nicotine at levels and speeds close to a cigarette. The authors of one study say the salt formulation may blunt the sensory cues that signal nicotine intake. In a small study of young adults in Poland, vapers scored higher on a dependence test than smokers. The reasons are not settled, and the studies are small.
Does a vape session end as naturally as a cigarette?
Not in the same way. A cigarette is a fixed unit that burns down. In a small study of Italian users, e-cigarette sessions averaged about 18 minutes against about 5 for a cigarette, with about 59 puffs against 17. The authors say device operation may explain part of that difference, so treat it as one data point.
Is nicotine replacement a good way to quit vaping?
The evidence is thin. NRT has trial evidence for quitting cigarettes, but the trials of NRT for vaping are small or short, and the largest one we found did not show a significant benefit over coaching calls. Talk to your doctor or pharmacist about whether NRT fits your situation.
How should I plan a quit if the evidence is unclear?
Plan for the nicotine and the habit together. RACGP guidance says the first-line approach to vaping is behavioural support, with medicine when it is needed, and that the aim is to become nicotine free. Count your puffs, set a step-down plan, and expect cravings. Talk to your doctor or pharmacist before you use any medicine.
References#
- Cross-category puffing topography, mouth level exposure and consumption study among Italian users of tobacco and nicotine products. Scientific Reports, 2019. www.nature.com/articles/s41598-019-55410-5
- Hajek P, et al. Nicotine delivery and users' reactions to a pod e-cigarette compared with cigarettes and other e-cigarette products (title shortened). Addiction, 2020. PubMed Central, PMC7318270. pmc.ncbi.nlm.nih.gov/articles/PMC7318270/
- E-Cigarettes are More Addictive than Traditional Cigarettes: A Study in Highly Educated Young People. PubMed Central, PMC6651627 (2019). www.ncbi.nlm.nih.gov/pmc/articles/PMC6651627/
- Hartmann-Boyce J, et al. Nicotine replacement therapy versus control for smoking cessation. Cochrane Database Syst Rev. 2018;5:CD000146. pubmed.ncbi.nlm.nih.gov/29852054/
- Royal Australian College of General Practitioners. Supporting smoking and vaping cessation, Part 2: Vaping cessation (September 2024). www.racgp.org.au/getmedia/924ba55d-dc47-41f9-bf5b-7a4cf9e19963/RACGP-NVP-and-Vaping-Cessation-September-2024.pdf.aspx
- Zolotarova T, et al. Vaping cessation interventions: a narrative review of randomized controlled trials. Tob Prev Cessat. 2026;12:10. pmc.ncbi.nlm.nih.gov/articles/PMC13397674/
- Evins AE, et al. Varenicline for Youth Nicotine Vaping Cessation: A Randomized Clinical Trial. JAMA. 2025. PubMed 40266580. pubmed.ncbi.nlm.nih.gov/40266580/
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